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Stabilization of biomolecules by attachment of responsive polymers and sensors thereof
专利权人:
FLIR Detection; Inc.
发明人:
Jeremy P. Walker,David C. Wilson,Anna M. Leech,Jessica J. Sinclair
申请号:
US14581203
公开号:
US10808238B2
申请日:
2014.12.23
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides a biomolecule conjugate having one or more functionalized biomolecules wherein the biomolecule is functionalized with one or more reactive sites, and at least one polymer capable of undergoing a polymer growth reaction, wherein the polymer is attached to at least one of the reactive sites of the functionalized biomolecule and wherein the polymer envelopes the functionalized biomolecule to form a reversible nanoparticle structure which protects the biomolecule by dynamically collapsing to preserve the biomolecule when an adverse environmental stimulus is present. A method of protecting a biomolecule from environmental conditions is also provided.
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