Sustained-release systems and methods of preparation of the active ingredient

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专利权人:

ユニバーシテ・ドゥ・モンペリエ・１;セントレ・ナショナル・デ・ラ・レシェルシェ・サイエンティフィーク

发明人:

ミシェル・ヴェール,ローラン・ルクレルク,マフード・ブッタ

申请号：

JP2010516541

公开号：

JP5650527B2

申请日:

2008.07.18

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

A system for controlled release of an active principle, includes at least (a) a degradable polymer matrix which produces acid compounds and (b) at least one acid-sensitive complex of an active principle having at least one electrostatic charge and a complexing polyelectrolyte partner of opposite charge which complexes with the active principle. A method for preparation of such a system is described. The release of the active principle (7P) is prolonged over 18 days (ternary system PMLA/7P/PLAGA) in comparison to binary systems (7P/PLAGA) and (PMLA/7P).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/