The present invention provides a tissue preservation sol ution that has good quality for preservation of tissues, org ans and cells, and is useful in the fields of regenerative m edicine, transplantation medicine, etc. The tissue preserva tion solution of the present invention comprises a compound having a Nrf2 activating effect. Preferable compounds havin g a Nrf2 activating effect are electrophiles, and in particu lar, ebselen and tert-butylhydroquinone. A preferable basal solution of the tissue preservation solution is Hank's bala nced salt solution.