COMPOUND, PHARMACEUTICAL COMPOSITION, METHODS TO INHIBIT INTRACELLULAR ADHESION MEDIATED BY SELECTIN, AND TO TREAT OR PREVENT DISEASE OR DISORDER IN A MAMMALIAN, AND USE OF A COMPOUND.
KRISTIN MARIE JANZ,ADRIAN HUANG,ALESSANDRO FABIO MORETTO,PATRICIA WARD BEDARD,NEELU KAILA
申请号:
BRPI0809509
公开号:
BRPI0809509A2
申请日:
2008.03.28
申请国别(地区):
BR
年份:
2014
代理人:
摘要:
The present teachings relate to novel compounds of formula I: wherein the constituent variables are as defined herein. Compounds of the present teachings can act as antagonists of the mammalian adhesion proteins known as selecting. Methods for treating or preventing selectin-mediated disorders are provided, which include administration of these compounds in a therapeutically effective amount.