JAMES FRANCIS CALLAHAN,GUOLIANG LIN,ZEHONG WAN,HONGXING YAN
申请号:
BRPI0908075
公开号:
BRPI0908075A2
申请日:
2009.02.05
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
The present invention is directed to novel compounds of Formula (I), pharmaceutical compositions and their use in therapy, for example as inhibitors of phosphodiesterase type IV (PDE4) and as antagonists of muscarinic acetylcholine receptors (mAChRs), in the treatment of/and or prophylaxis of respiratory diseases, including antiinflammatory and/or allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma, rhinitis (e.g. allergic rhinitis), atopic dermatitis or psoriasis.