ABSTRACT - 600649 The disclosure relates to an anti-infective device comprising: (i) a catheter comprising a non-luminal exterior surface and a lumen surface and (ii) an anti-infective composition comprising at least one polymer which is a cellulose or cellulose-derived polymer and a pyrimidine analog, wherein the pyrimidine analog is selected from the class consisting of 5-fluorouracil and floxuridine wherein the anti-infective composition is located on the exterior surface and not on the lumen surfaceand wherein the catheter may be formed from a polymeric material, the anti-infective composition being on the catheter in the form of a coating having a substantially uniform average thickness, the average thickness ranging from 0.5 (m to 10 (m.
