The Invention relates to benzoxazoles replaced formula I and to processes for their Preparation and their use for the preparation of medicaments for the prophylaxis and \/ or treatment of diseases, particularly cardiovascular disorders, preferably of thrombotic or thromboembolic Disorders You. Where is a formula: R1 to R7), etc. is H or c1-c6 alkyl. R8 is H.Preferred compounds are: (2 - ((1S) - 1 - (3-chlorophenyl) - 2 - fluoroetil] amino} 7 - methoxy - 1.3 - benzoxazole il) - 5 - [(2S, 5S) - 5 - (2-hydroxyethyl) - 2 - 4 - sulfate] methanone (IL 2 - [(1S) - 1 - (3-chlorophenyl) - 2 - fluoroetil] amino} 7 - methoxy - 1.3 - benzoxazole il) - 5 - [(2S, 5S) - 5 - (2-hydroxyethyl) - 2 - 4 - il] methanone sulfateLa invencion se refiere a benzoxazoles sustituidos de formula I y a procesos para su preparacion y a su uso para la preparacion de medicamentos para el tratamiento y/o profilaxis de enfermedades, en particular de trastornos cardiovasculares, preferiblemente de trastornos tromboticos o tromboembolicos. Donde: R1 es una formula a), etc. R7 es H o alquilo C1-C6. R8 es H. Son compuestos preferidos: (2-{[1S)-1-(3-clorofenil)-2-fluoroetil]amino}7-metoxi-1,3-benzoxazol-5-il)[2S,5S)-5-(2-hidroxietil)-2-metilmorfolin-4-il]metanona (2-{[1S)-1-(3-clorofenil)-2-fluoroetil]amino}7-metoxi-1,3-benzoxazol-5-il)[2S,5S)-5-(2-hidroxietil)-2-metilmorfolin-4-il]metanona
