Disclosed are an intelligent bionic expectoration system and a three-way device thereof, wherein the intelligent bionic expectoration system comprises a negative pressure suction module, a central processing module, a patient interface unit and a respiratory muscle synchronous motion module. The central processing module controls two valves to open or close, closing one valve while opening another valve, and controls the respiratory muscle synchronous motion module； the patient interface unit is connected to the positive pressure ventilation module and the negative pressure suction module, allowing positive pressure airflow or negative pressure airflow to flow by, depending on which valve is open, so as to allow airflow to flow in or out of the lung. The respiratory muscle synchronous motion module can employ nerve stimulation, for example, diaphragm pacing, can also employ mechanical pushing, and the effects of both are making the respiratory muscle produce specific actions corresponding to inspiration or expiration. The respiratory muscle synchronous motion module is connected to the central processing module, and under the control of the central processor, acts synchronously as the airflow moves, thereby simulates human coughing in an even better fashion, and achieves bionic expectoration. The three-way device comprises a chamber (1), a gas-guide tube (2), a commutation assembly (3), an electrical energy driving means (4), and a body frame (5), and controls the circulation of the air pressure generated by a fan blower.
