Laura Martinson,Evert Kroon,Kevin D'Amour,Emmanuel Edward Baetge,Kevin DAmour
申请号:
US14670249
公开号:
US20150265657A1
申请日:
2015.03.26
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Disclosed herein are methods of producing pancreatic hormone-expressing cells by first differentiating pluripotent cells in cell culture so as to produce endodermal cells, the endodermal cells being competent to further differentiate into hormone-expressing cells capable of secreting at least one pancreatic hormone in response to a physiological signal, and then, transplanting the cultured endodermal cells into an organism, such as an organism in need of an endocrine cell therapy.