A liquid composition suitable for topical use comprising is provided that includes a phospholipid foaming agent and at least one solvent； and a pharmaceutically acceptable active agent； wherein the liquid composition is capable of mechanically foaming without an additional propellant； and wherein upon mechanical foaming of 250 ml of the liquid composition results in a foam with a foam volume of at least about 400 ml and a foam stability wherein at least about 50% of the foam volume is still present after about 5 minutes at 25° C., as determined using a SITA foam measurement. Also provided herein are methods of making disclosed compositions and methods of use.
