METHOD FOR THE PREPARATION OF (4S) 4 (4 CYANO 2 METHOXYPHENYL) 5 ETHOXY 2 8 DIMETHYL 1 4 DIHYDRO 1 6 NAPHTHYRIDINE 3 CARBOXAMIDE AND THE PURIFICATION THEREOF FOR USE AS AN ACTIVE PHARMACEUTICAL INGREDIENT
The present invention relates to a novel and improved method for the preparation of (4S) 4 (4 cyano 2 methoxyphenyl) 5 ethoxy 2 8 dimethyl 1 4 dihydro 1 6 naphthyridine 3 carboxamide of the formula (I) and of a crystalline modification of said compound.