Athwal, Diljeet Singh,Brown, Derek Thomas,Weir, Andrew Neil Charles,Chapman, Andrew Paul,King, David John,Popplewell, Andrew George
申请号：
DK10010795
公开号：
DK2308975T3
申请日:
2001.06.05
申请国别(地区):
DK
年份:
2016
代理人:
摘要：
There is disclosed antibody molecules containing at least one CDR derived from a mouse monoclonal antibody having specificity for human TNF±. There is also disclosed a CDR grafted antibody wherein at least one of the CDRs is a hybrid CDR. Further disclosed are DNA sequences encoding the chains of the antibody molecules, vectors, transformed host cells and uses of the antibody molecules in the treatment of diseases mediated by TNF±.
