Disclosed are devices and methods for treating and disinfecting a surface that is also useful for the treatment of patients. Compositions, including antiseptic compositions, that can be used for the methods are also disclosed. In particular, invention provides an improved antiseptic With improved efficacy against COVID-19. One benefit of the disclosed methods and compositions is that it is effective even When used for very short contact times. The composition of the invention comprises an antiseptic and a cellulosic polymer.