The liquid of microwave sterilization machine disinfection includes that resonant cavity (1) and process chamber (3) are partly located at the resonant chamber (1). Resonant cavity (1) main body (2) and process chamber (3) are (4) with a lid. Resonant cavity (1) includes body member (2), process chamber (3) and process chamber (3) lid (4). Magnetron (5,6) is connected to resonant cavity (1) body (2). The magnetron (5,6) of antenna (7) is put into the inside (1) of chamber. Container (8) sterilizes comprising liquid material. Resonant cavity (1) body (2) upper flange (11) is by peripheral sealing (12) around the sealing of the wall (3) of cylindrical process chamber (3) contact and the flange (11) and process chamber.