SI CHUAN UNIVERSITY;CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD.
发明人:
YANG, SHENGYONG,WEI, YUQUAN
申请号:
EP10851938
公开号:
EP2578584A4
申请日:
2010.12.23
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
Arylamino purine derivatives represented by formula I and their preparation method are disclosed, wherein each substituent is defined as in the description. The derivatives have an inhibitory effect on non-small cell lung cancer with deletion mutation of exon 19 or L858R point mutation of exon 21 in epidermal growth factor receptor (EGFR).