TROFIMOV, Aleksandr Vladislavovich,KHAVINSON, Vladimir Khatskelevich,IVKO, Oleg Mikhailovich,TROFIMOVA, Svetlana Vladislavovna
申请号：
AU2017439352
公开号：
AU2017439352B2
申请日:
2017.11.08
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
The present invention proposes a new use of dipeptide L-glutamic-L-tryptophan acid (L-Glu-L-Trp) as a means for enhancing tissue oxygenation by suppression (reducing a synthesis) of HIF-1α factor in case of diabetic foot, a medical preparation, comprising an effective amount of said dipeptide L-Glu-L-Trp as the active agent and a pharmaceutically acceptable carrier and a method of treatment a diabetic foot consisting of a local administration the mentioned medical preparation comprising the dipeptide L-Glu-L-Trp in the dose of 1.0-10.0 μg per kg of body weight at least once a day for a period which is necessary for achieving the therapeutic effect. Technical result of invention consists in providing a peptide preparation, which exerts an antihypoxic effect in diabetes mellitus of both types.
