This invention relates to an inflammation and sore resistant medicine for oral soft tissue (gum, mucous membrane) which is a mixture containing one or more adrenocorticotropic hormones or anti-inflammatory inhibiting compounds, one or more adhesive polymers having long term adhesion, one filling and repairing agent, and one or more additives, wherein the content of adrenocorticotropic hormones or anti-inflammatory inhibiting compounds is 0.5-2 mass percent the content of the adhesive polymers is 1-4.5 mass percent the content of the filling and repairing agent is 35-45 mass percent the content of the additives is 30-50 mass percent and the potential of hydrogen value index (PH) of the mixture is 6-8.5.一種口腔軟組織(牙齦、黏膜)抗發炎酸痛劑,係包含有:一種以上促腎上腺皮質激素或抗炎抑制化合物、具長效黏附性之一種以上黏合聚合物、一種填補修護劑以及一種以上添加劑混合而成一混合物;其中前述促腎上腺皮質激素或抗炎抑制化合物含量為0.5~2質量百分比;前述黏合聚合物含量為1~4.5質量百分比;前述填補修護劑含量為35~45質量百分比;前述添加劑含量為30~50質量百分比,前述混合物的酸鹼值指數PH6~8.5。