CHEN, CHIA HUNG,陈嘉宏,陳嘉宏,WANG, CHAU HUI,王朝晖,王朝暉,LIN, JOHN SON,林炯森,林炯森,CHIU, TIEH-HSIUNG,邱铁雄,邱鐵雄,CHEN, JING YI,陈静仪,陳靜儀,LIAO, PI HUNG,廖碧虹,廖碧虹,SU, CHIA CHI,苏家琪,蘇家琪,LIAO, WEI CHUAN,廖伟全,廖偉全
申请号：
TW101143626
公开号：
TW201408335A
申请日:
2012.11.22
申请国别(地区):
TW
年份:
2014
代理人:
摘要：
This invention provides a metal-chelating complex micelle loaded with antioxidants, which are used for reducing the damage of free radicals. The composition contains at least one metal or its ion, at least one drug or carrier-protected or modified antioxidant, and a drug carrier. The invented carrier can maintain the potency of drug or antioxidant, thus prolonging its duration of effectiveness. It could be applied for reducing radiation damages and the adverse (side) effects of chemotherapy.本發明係提供一種降低自由基傷害之複合微胞載體醫藥組成物,該組成物包含:至少一金屬或其離子;至少一藥物或受載體保護及修飾的抗自由基氧化物;及一藥物載體。本發明之載體可保存藥物或抗氧化物之活性,使其不易被環境或體液內的天然自由基降低效力,達到延長保護力的效果,可應用於減輕輻射傷害與化療藥物副作用。100‧‧‧載體110‧‧‧抗氧化物或其他類似藥物120‧‧‧金屬或金屬離子
