PROBLEM TO BE SOLVED: To provide a novel constriction inhibitor which can inhibit constriction.SOLUTION: The present invention provides a constriction inhibitor comprising a culture supernatant of mesenchymal cells, and a composition comprising a culture supernatant of CD90 expression positive mesenchymal cells and having a viscosity of 100 cP or more and 1000000 cP or less.SELECTED DRAWING: NoneCOPYRIGHT: (C)2017,JPO&INPIT【課題】狭窄を抑制することができる新規な狭窄抑制剤を提供すること。【解決手段】間葉系細胞の培養上清を含む狭窄抑制剤、並びにCD90の発現が陽性である間葉系細胞の培養上清を含み、粘度が100cP以上1000000cP以下である、組成物。【選択図】なし