BUNIATIAN, GAYANE,GEBHARDT, ROLF,GLEITER, CHRISTOPH,DANIELYAN, LUSINE,PROKSCH, BARBARA
申请号：
CA2699624
公开号：
CA2699624C
申请日:
2008.04.18
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The present invention relates to a method for the treatment of organs which are degenerative and /or in the pathological state by means of the use of cells, which are phenotypically stably differentiating or differentiated but not necessarily ultimately predetermined with respect to development, from a donor organ selected according to the principles of the opposite cell differentiation program (OCDP) and also to the use of cells of this type for the treatment or for the production of a drug for treatment of the same. Furthermore, the present invention relates to pharmaceutical agents comprising suitable phenotypically stable cells, cells of a first organ which is different from the second organ with respect to organ type thereby being used, which, in the normal physiological state with respect to a predetermined set of expressed genes and/ or phenotypical properties, have opposite properties to the second cells in the normal physiological state.
