The Research Foundation for The State University of New York;Baxalta Incorporated;Baxalta GmbH;Brookhaven Science Associates LLC
发明人:
申请号：
EP19217974.5
公开号：
EP3705133A2
申请日:
2011.05.13
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The invention relates to the development of chimeric OspA molecules for use in against Lyme disease or borreliosis vaccine. More specifically, the chimeric OspA molecules comprise the proximal portion from one OspA serotype, together with the distal portion from another OspA serotype, while retaining antigenic properties of both of the parent polypeptides. The chimeric OspA molecules are delivered alone or in combination to provide protection against a variety of Borrelia genospecies.
