JUHL, Martin,JENSEN, Klaus Gjervig,KVÆRNØ, Lisbet,JORGENSEN, Morten
申请号：
CL2020001343
公开号：
CL2020001343A1
申请日:
2020.05.20
申请国别(地区):
CL
年份:
2020
代理人:
摘要：
F amp； oacute； n provides F amp； compounds； oacute； rmula (I),They are: Ketamine (Prof amp)； Aacute； and Current inventions, including compounds of invention； ampere； ampere； ampere； ampere； anku； ampere； ampere； anku； medicinal materials, including the compounds of invention； ampere； amp； amp； ampere； anku； all persons treating neurodegenerative or neurogenic mental disorders and diseases； anku； using the compounds of invention and amp； triple therapy； anku； anku； Anhui； N, including diseases Parkinson's. So,1. The present invention refers to the compounds of F amp, oacute, rmula (ID), amp, NBS (ID). Among these compounds, R1 is h, R2 is the substitutes (I) and (II) selected from M amp, Aacute and S.； R1 is the substitutes (I) and (II) selected from M amp； Aacute, S. front and R2 are h； O both R1 and R2 are represented by M amp (I)； Aacute (s)； or R1 and R2 are represented by M amp (II)； Aacute (s)； or R1 is an alternative (I)； R2 is an alternative (II)； or R1 is a substitute (I)； and R2 is a substitute (II)；O R1 is the substitute (II) and R2 is the substitute (I)； amp； nbs, representing the point of uni amp； oacute, N, and AMP, Aacute, oacute, N, in the substitute (I), in EST amp, Aacute, in CI amp configuration, oacute, N, s, or salt and AMP, eacute, are effectively accepted by people.<；p>；La presente invenció；n proporciona compuestos de fó；rmula (I), que son profá；rmacos de catecolamina para uso en el tratamiento de enfermedades y trastornos neurodegenerativos. La presente invenció；n proporciona tambié；n composiciones farmacé；uticas que comprenden compuestos de la invenció；n y mé；todos de tratar enfermedades y trastornos neurodegenerativos o neuropsiquiá；tricos utilizando los compuestos de la invenció；n, en particular la enfermedad de Parkinson. Por consiguiente, la presente invenció；n se refiere a compuestos de fó；rmula (Id), ；(Id) donde R1 es H y R2 se selecciona
