LEE HYUNHO,CHUN KWANGWOO,JOE BO YOUNG,KIM EUN SEON,JANG EUN SUNG,OH HYEONGCHAN,KIM JEONG MIN,PARK JISEON,LEE HANCHANG
申请号：
IN201717043786
公开号：
IN201717043786A
申请日:
2017.12.06
申请国别(地区):
IN
年份:
2018
代理人:
摘要：
The present invention relates to a novel tricyclic derivative compound and more specifically to a tricyclic derivative compound having excellent inhibitory activity against PARP 1 tankyrase 1 or tankyrase 2 optical isomers thereof a racemate thereof or a pharmaceutically acceptable salt thereof. The tricyclic derivative compound optical isomers thereof racemate thereof or pharmaceutically acceptable salt thereof according to the present invention can be usefully used for the prevention or treatment of neuropathic pain neurodegenerative diseases cardiovascular diseases diabetic neuropathy inflammatory diseases osteoporosis or cancer through inhibitory activity against PARP 1 tankyrase 1 or tankyrase 2.
