PROBLEM TO BE SOLVED: To provide a technique for suppressing the precipitation of crystals of an aqueous composition comprising a halogenated isoquinoline derivative during storage at a low temperature.SOLUTION: An aqueous composition comprises a compound represented by general formula (1) in the figure, where X represents a halogen atom, or a salt thereof, or a solvate of them, and brimonidine or a salt thereof.SELECTED DRAWING: NoneCOPYRIGHT: (C)2016,JPO&INPIT【課題】ハロゲン化イソキノリン誘導体含有水性組成物の、低温保存時の結晶析出を抑制する技術の提供。【解決手段】次の一般式(1)[式中、Xはハロゲン原子を示す。]で表される化合物若しくはその塩又はそれらの溶媒和物、及びブリモニジン又はその塩を含有する、水性組成物。【選択図】なし