Drug synthesis and its preparation process for oral management, prevention and treatment of irritable bowel symphony, based on a change in intestinal motility and alpha-d-galactic enzymes
BERNARDO ESCUDERO, ROBERTO,SAVOIR VILBOEUF, JOHN CLAUDE
申请号：
PE2013001061
公开号：
PE20140379A1
申请日:
2011.11.15
申请国别(地区):
PE
年份:
2014
代理人:
摘要：
An oral drug component, such as a plate, coating plate, capsule, or powder, including (a) an agent that changes the intestinal dynamics, such as tributylbutylene, herring, ribavirin, Daphnia, etc.； and (b) a polymer, such as hydroxypropylcellulose, starch, maze, etc, Propylcellulose and methylcellulose, (c) diluents such as lactose, mannitol and microcrystalline cellulose, including (d) lubricants such as magnesium stearate, megalithic acid salt and estarico, (E) skateboards such as silicon crystal dioxide, and (f) fragments such as cropovine,Starch powder and croscarmelosa sodica, or suspensions such as microcrystalline cellulose and carbohydrate sodium and (g) α - d-galactase. A preparation method is also mentionedREFERIDA A UNA COMPOSICION FARMACEUTICA DE ADMINISTRACION ORAL EN FORMA DE UNA TABLETA, TABLETA RECUBIERTA, CAPSULA O POLVO PARA RECONSTITUIR QUE COMPRENDE: a) UN AGENTE MODIFICADOR DE LA MOTILIDAD INTESTINAL TAL COMO TRIMEBUTINA, ALOSETRON, MEBEVERINA, LOPERAMIDA, ENTRE OTROS, b) UN AGLUTINANTE TAL COMO HIDROXIPROPILCELULOSA, ALMIDON DE MAIZ, PROPILCELULOSA Y METILCELULOSA, c) UN DILUYENTE TAL COMO LACTOSA, MANITOL, CELULOSA MICROCRISTALINA, ENTRE OTROS, d) UN LUBRICANTE TAL COMO ESTEARATO DE MAGNESIO, TALCO Y ACIDO ESTEARICO, e) UN DESLIZANTE TAL COMO DIOXIDO DE SILICIO COLOIDAL, f) UN DESINTEGRANTE TAL COMO CROSPOVIDONA, ALMIDON DE MAIZ Y CROSCARMELOSA SODICA O UN AGENTE SUSPENSOR TAL COMO CELULOSA MICROCRISTALINA Y CARBOXIMETILCELULOSA SODICA Y g) LA ENZIMA ALFA-D-GALACTOSIDASA. TAMBIEN ESTA REFERIDA A UN METODO DE PREPARACION
