#$%^&*AU2018203000A120180517.pdf#####ABSTRACT Edema in tissue of a patient undergoing a course of radiation therapy or treatment can be estimated based on one or more MRI measurements used to measure changes in fluid content of various tissues. A correlation between observed changes in edema and one or more delivered fractions of radiation can be used to drive one or more clinical actions. Methods, systems, articles of manufacture, and the like are described.WO 20 14/066853 PCT/US2013/066963 1/9 1O co co NN ICC) ...... (N.O