A composition is described wherein metal is chelated by a complexing agent such as a pyrithione or certain other thiol compounds in the form of a metal: complexing agent complex, wherein the metal is selected from the group consisting of bismuth, arsenic and antimony. Methods for using the composition as a bacteriocidal, bacteriostatic. antibiofilm, antifungal, and antiviral agent and as a disinfectant and preservative are also provided.