Use of phenylephrine hydrochloride (or a pharmaceutically acceptablealternative form of phenylephrine) andparacetamol in the production of a combination medicament for treating upperrespiratory mucosal congestion, comprisingcombining such substances with excipients, characterised in that themedicament has the phenylephrine hydrochloride(or the pharmaceutically acceptable alternative form of phenylephrine) andparacetamol in proportions suitable for, and the medicament is for, providingan adult with: a) 4 mg - 7.5 mg phenylephrine hydrochloride (or an equivalentamount of a pharmaceutically acceptable alternativeform of phenylephrine), in combination with 950 mg - 1,000 mg paracetamol; orb) 5 mg - 7.5 mg phenylephrine hydrochloride (oran equivalent amount of a pharmaceutically acceptable alternative form ofphenylephrine), in combination with 600 mg - 700 mgparacetamol; or c) 6 mg - 8 mg phenylephrine hydrochloride (or an equivalentamount of a pharmaceutically acceptable alternativeform of phenylephrine), in combination with 500 mg - 550 mg paracetamol.