Daniel OLIVE;Marc BONNEVILLE;Emmanuel SCOTET;Christelle HARLY;Yves GUILLAUME
发明人:
Daniel OLIVE,Marc BONNEVILLE,Emmanuel SCOTET,Christelle HARLY,Yves GUILLAUME
申请号:
US14791528
公开号:
US20150353643A1
申请日:
2015.07.06
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Described herein are anti-CD277 antibodies which: activates or inhibit the cytolytic function of Vγ9/Vδ2 T cells, and/or costimulates T cells together with CD3-TCR, and/or costimulates T cells in addition to CD28-B7 costimulation, and/or increases the activity and/or survival of monocytes and dendritic cells. The use of said antibodies in therapy is also described.