Adjuvanted formulations of staphylococcus aureus antigens

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专利权人:

Novartis AG

发明人:

Bagnoli, Fabio,Baudner, Barbara,Bufali, Simone

申请号：

AU2012300765

公开号：

AU2012300765A1

申请日:

2012.08.31

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

The efficacy of S.aureus vaccines can be enhanced by adjuvanting S.aureus antigens with a mixture of a TLR agonist (preferably a TLR7 agonist) and an insoluble metal salt (preferably an aluminium salt). The TLR agonist is typically adsorbed to the metal salt. A S.aureus antigen can also be adsorbed to the metal salt.

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