HAWKINS, LYNN,BOIVIN, ROCH,HANSEN, HANS,ISHIZAKA, SALLY,MACKEY, MATTHEW,SCHILLER, SHAWN,OGAWA, CHIKAKO,NARAYAN, SRIDHAR,BERTINATO, PETER,BERGER, GREGORY,ENDO, ATSUSHI,YU, ROBERT T.
申请号:
CA2920791
公开号:
CA2920791A1
申请日:
2014.10.14
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
Embodiments of the disclosure relate to selectively substituted quinoline compounds of formula (I) that act as antagonists or inhibitors for Toll -like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.