PROCÉDÉ DE FABRICATION DE FEUILLET CELLULAIRE MULTICOUCHE, FEUILLET CELLULAIRE MULTICOUCHE AYANT UN RÉSEAU VASCULAIRE OBTENU PAR LE PROCÉDÉ, PROCÉDÉ D'UTILISATION DE CELUI-CI
A method for manufacturing a multilayered cell sheet characterized in: fabricating a vascular bed that constructs a vascular network extending to the surface from a channel for perfusing a medium, the channel being embedded in a gel; and layering a cell sheet onto the vascular bed to construct a vascular network in the cell sheet. This manufacturing method makes it possible to construct a vascular network in the cell sheet and to fabricate a thick multilayered cell sheet in a simple manner by layering cell sheets. Such a thick multilayered cell sheet is useful as an in-vivo tissue substitute in regenerative medicine involving a variety of tissues.