SCHLACHTER, Kelly W.,VASQUEZ, Erick,SHIMKO, Daniel A.
申请号：
EP17744706
公开号：
EP3407924A4
申请日:
2017.01.19
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
A method of making an electron beam irradiated osteoinductive implant is provided. The method comprises exposing an osteoinductive implant containing demineralized bone matrix (DBM) fibers to electron beam radiation at a dose of from about 10 kilograys to 100 kilograys for a period of time. The electron beam irradiation reduces microorganisms in the osteoinductive implant, and the electron beam irradiated osteoinductive implant retains osteoinductive properties. Methods of implantation and an irradiated osteoinductive implant are also disclosed.
