CEDARS-SINAI MEDICAL CENTER;YEDA RESEARCH AND DEVELOPMENT, CO., LTD.
发明人:
KORONYO, MAYA,BLACK, KEITH L.,SCHWARTZ, MICHAL,FARKAS, DANIEL L.,KORONYO, YOSEF
申请号：
CA2735869
公开号：
CA2735869C
申请日:
2009.09.18
申请国别(地区):
CA
年份:
2020
代理人:
摘要：
The present subject matter relates to anon-invasive optical imaging method for monitoringear-ly pathological events specific to Alzheimer's disease(AD), such as the development, amount and location ofamyloid plaques. The ability to monitor such eventspro-vides a basis for, among other things, AD diagnosis,prognosis and assessment of potential therapies. Inaddi-tion, the present subject matter introduces novel methodsfor treating AD and retinal ailments associated with AD.A.beta.-plaque detection in living brains is extremely limited,especially at high resolution； therefore the presentinven-tion is based on studies focusing on the eyes as analter-native to brain-derived tissue that can be imageddirect-ly, repetitively and non-invasively.
