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ESLICARBAZEPINE ACETATE AND WAYS OF ITS APPLICATION
专利权人:
С.А. (PT);БИАЛ-ПОРТЕЛА ЭНД КА
发明人:
ВЬЕЙЕРА АРАУЖУ СУАРИШ ДА СИЛВА Патрисио Мануэл (PT),ДЕ АЛМЕЙДА Жозе Луиш (PT)
申请号:
RU2010154008/15
公开号:
RU2010154008A
申请日:
2010.12.28
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
1. The use of eslicarbazepine acetate for the manufacture of a pharmaceutical composition comprising a pharmaceutically effective amount of eslicarbazepine acetate for the treatment of affective disorders, schizoaffective disorders, bipolar disorders, attention disorders, anxiety disorders, migraines, neuropathic pain and disorders associated with neuropathic pain, sensory motor disorders or changes in the activity of the nervous system in degenerative and postischemic disorders, where the specified fa The pharmaceutical composition is intended to be administered once a day. ! 2. The use according to claim 1, where the pharmaceutically effective amount is administered in an amount that provides the maximum observed plasma concentration, Cmax, eslicarbazepine of more than approximately 7400 ng / ml. ! 3. The use of claim 2, wherein the pharmaceutically effective amount is administered in an amount providing a Cmax of eslicarbazepine of greater than about 12,000 ng / ml. ! 4. The use according to claim 1, where the pharmaceutically effective amount is administered in an amount providing an area under the concentration curve, AUC0-τ, of eslicarbazepine of more than about 111,000 ng · h / ml, where τ is the interval between doses of the drug. ! 5. The use according to claim 4, where the pharmaceutically effective amount is administered in an amount providing AUC0-τ of eslicarbazepine of more than approximately 140,000 ng · h / ml. ! 6. The use according to any one of the preceding paragraphs, where the pharmaceutically effective amount is at least about 400 mg of eslicarbazepine acetate. ! 7. The use according to claim 6, where the pharmaceutical1. Применение эсликарбазепина ацетата для изготовления фармацевтической композиции, включающей фармацевтически эффективное количество эсликарбазепина ацетата для лечения аффективных расстройств, шизоаффективных расстройств, биполярных расстройств, расстройств внимания, тревожных расстройств, мигрени, невропатической боли и расст
来源网站:
中国工程科技知识中心
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