Henry, William,Wolf-Garraway, Richard,Mayo, John Charles,Earl, Michael James
申请号:
AU2013248296
公开号:
AU2013248296A1
申请日:
2013.04.16
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
Methods and dosage formulations are provided for subcutaneous administration in which therapeutic agents are modified to increase the hydrophilicity and molecular dimensions in relation to the native state of the therapeutic agent, in which the Cmax:Caverage ratio is lower than the Cmax:Caverage ratio of the agent when delivered intravenously.