INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE;UNIVERSITÉ DE BRETAGNE OCCIDENTALE;CENTRE HOSPITALIER RÉGIONAL ET UNIVERSITAIRE DE BREST
发明人:
Paul-Alain Jaffrès,Hélène Couthon-Courvès,Damien Afonso,Tristan Montier,Tony Le Gall
申请号：
US15761350
公开号：
US10676492B2
申请日:
2016.09.23
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Disclosed are novel branched amphiphilic lipids, in particular novel branched amphiphilic lipids of general formula (II). Also disclosed is a method of synthesis for the compounds of formula (II), from unsaturated amphiphilic compounds of general formula (I). Further disclosed is the use of the compounds of general formula (II) and of the lipoplexes obtained by formulation of the compounds of general formula (II) for applications, particularly transfection, in which improved fusion properties are desired.
