The United States of America; as represented by the Secretary; Department of Health & Human Servic
发明人:
Wan-Ju Li,Leon J. Nesti,Rocky S. Tuan
申请号：
US14981332
公开号：
US20160106548A1
申请日:
2015.12.28
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The instant invention is directed to a tissue engineered intervertebral disc comprising at least one inner layer and an exterior layer, wherein: the exterior layer comprises a nanofibrous polymer support comprising one or more polymer nanofibers； the at least one inner layer comprises a hydrogel composition comprising at least one or more hydrogel materials and/or one or more polymer nanofibers； and a plurality of cells which are dispersed throughout the tissue engineered intervertebral disc. Additionally, the instant invention is directed to methods of making such intervertebral discs and methods of treating intervertebral disc damage.
