This invention relates to Hendra and Nipah immunogenic compositions and methods of use. The invention also relates to methods of distinguishing subjects vaccinated with the immunogenic compositions of the invention from those infected with Hendra and/or Nipah virus.本發明係關於亨德拉(Hendra)及立百(Nipah)免疫原組合物及使用方法。本發明亦關於區分使用本發明之免疫原組合物疫苗接種之個體與感染亨德拉及/或立百病毒者之方法。