A skin care fabric for medical, pharmaceutical or cosmetic use includes at least 80% by weight of microfibers whose fibers have a diameter of less than 50 microns and are a mixture of polyamide and polyester, wherein the fabric has been subjected to a splitting process by a alkaline solution treatment, splitting each microfiber producing fine fibers closely packed in a parallel structure having a capillary effect and an abrasive effect. The fabric has a surface weight of less than 180 g/m2 and is loaded with medical, pharmaceutical or cosmetic active agents. The fabric is a warp-knitted fabric having a first surface on one opposite side and a second surface on the other opposite side, wherein the first surface is mechanically roughened and cut making it fluffy and yet short-haired compact in order to leave as few loose fibers as possible on the skin during use and resulting in a further surface enlargement of the fabric structure, having a water absorbency of at least four times the surface weight of the fabric.