Method for the preparation of high-purity pharmaceutical intermediates

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专利权人:

Gyula Simig;Gyorgyi Kovanyine Lax;Gyorgy Krasznai;Kalman Nagy;Gabor Bagyinszki;Ferenc Lorant Bartha;Jozsef Barkoczy;Eva Sipos;Adrienn Keszthelyi;Janos Imre;Balazs Volk;Gyorgy Ruzsics;Gyorgy Morovjan

发明人:

Gyorgyi Kovanyine Lax,Gyula Simig,Balazs Volk,Ferenc Lorant Bartha,Gyorgy Krasznai,Gyorgy Ruzsics,Eva Sipos,Kalman Nagy,Gyorgy Morovjan,Jozsef Barkoczy,Adrienn Keszthelyi,Janos Imre,Gabor Bagyinszki

申请号：

US13990283

公开号：

US09133132B2

申请日:

2011.11.29

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present invention is related to intermediates useful in the preparation of pharmaceutically acceptable salts of (+)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)-pyrimidin-5-yl]-(3R,5S)-dihydroxy-hept-6-enoic acid and polymorphs of said intermediates, methods for preparation thereof and use thereof.

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http://www.ckcest.cn/home/