Sudhir Agrawal;Tao Lan;Mallikarjuna Reddy Putta;Ekambar R. Kandimalla;Dong Yu;Daqing Wang;Yukui Li
发明人:
Ekambar R. Kandimalla,Tao Lan,Yukui Li,Dong Yu,Daqing Wang,Mallikarjuna Reddy Putta,Sudhir Agrawal
申请号：
US11697422
公开号：
US08106173B2
申请日:
2007.04.06
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to the therapeutic use of stabilized oligoribonucleotides as immune modulatory agents for immune therapy applications. Specifically, the invention provides RNA based oligoribonucleotides with improved nuclease and RNase stability and that have immune modulatory activity through TLR7 and/or TLR8.
