CHILDREN'S HOSPITAL MEDICAL CENTER;CHILDRENS HOSPITAL MEDICAL CENTER
发明人:
SHIVAKUMAR, PRANAV-KUMAR
申请号:
CA2986957
公开号:
CA2986957A1
申请日:
2016.05.24
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Disclosed are methods and compositions for treatment of a subject having a biliary disorder. The methods include administering a therapeutically effective amount of a serine protease inhibitor to a subject in need thereof. The biliary disorder may include biliary atresia, a biliopathy, Primary Biliary Cirrhosis (PBC), Primary Sclerosing Cholangitis (PSC), and combinations thereof. In certain aspects, the serine protease inhibitor may be a protease inhibitor rC1 Inhibitor.