The present disclosure specifically provides compositions that bind soluble biomolecules and inhibit their biological activity, as well as pharmaceutical compositions thereof. Many applications where the composition is useful (eg, therapeutic applications) are also provided herein. [Selection] Figure 2本開示は、特に、可溶性生体分子と結合し、その生物学的活性を阻害する組成物並びにその医薬組成物を提供する。本組成物が有用な多くの適用(例えば、治療的適用)も本明細書において提供される。【選択図】図2