A system for sensing glucose concentration is provided and includes following units. A light source generates a light beam. A polarization state generator (PSG) includes a modulator for changing the polarization of the light beam, and then the light beam is emitted to a biological tissue. A polarization state analyzer (PSA) receives the light beam which is reflected from the biological tissue. A control module transmits an electrical signal to the modulator. The electrical signals includes at least 4 sampling points which are corresponding to different polarization, and each sampling point is used to calculate a corresponding stokes vector. The control module calculates a Mueller matrix according to the stokes vectors, calculates at least one parameter according to the Mueller matrix, and then calculates a glucose concentration corresponding to the biological tissue according to the parameter.一種葡萄糖濃度的感測系統,包括以下元件。光源用以產生光線,偏振狀態產生器包括調變器以改變光線的偏振狀態,之後光線用以射向生物組織。偏振狀態分析器用以接收由生物組織反射的光線。控制模組用以傳送電子訊號至調變器。此電子訊號具有至少4個取樣點,這些取樣點分別對應至不同的偏振狀態,每一個取樣點都可用來計算出對應的史托克斯向量。控制模組根據這些史托克斯向量計算出穆勒矩陣,根據穆勒矩陣計算出至少一參數,並根據參數計算出對應於生物組織的葡萄糖濃度。100‧‧‧感測系統110‧‧‧光源111‧‧‧光線120‧‧‧偏振狀態產生器121‧‧‧偏振板122‧‧‧光電調變器123‧‧‧四分之一波片124‧‧‧二分之一波片130‧‧‧生物組織140‧‧‧偏振狀態分析器141‧‧‧光電調變器142‧‧‧光電調變器143‧‧‧分析器144‧‧‧偵測器150‧‧‧控制模組151‧‧‧連接器152‧‧‧電腦系統153‧‧‧波形產生器154~156‧‧‧光電驅動器161‧‧‧電子訊號
