The present disclosure provides binding proteins, such as antibodies, that bind to a GDNF Family Receptor Alpha Like (GFRAL) protein, including human GFRAL protein, and methods of their use.本發明提供結合蛋白質,諸如抗體,其結合於GDNF家族受體α類(GFRAL)蛋白質,包括人類GFRAL蛋白質,及其使用方法。