Philip D. Gregory,Jeffrey C. Miller,David Paschon,Edward J. Rebar,Siyuan Tan,Fyodor Urnov,Lei Zhang
申请号：
US15709969
公开号：
US20180010152A1
申请日:
2017.09.20
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also disclosed are methods of using these novel DNA-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences.
