University of Utah Research Foundation;The Walter and Eliza Hall Institute of Medical Research
发明人:
MENTING, John Gerbrandt Tasman,SMITH, Brian,CHOU, Danny Hung-Chieh,SAFAVI-HEMAMI, Helena,LAWRENCE, Michael Colin,BALDOMERO, Olivera M.
申请号:
EP17830123
公开号:
EP3487876A4
申请日:
2017.07.21
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present invention relates to insulin analogs, particularly insulin analogs having shortened B chains. The present invention also relates to the crystal structure of insulin from the venom of cone snails and to methods of using the crystal and related structural information to screen for and design insulin analogs that interact with or modulate the insulin receptor. The present invention also relates to therapeutic and prophylactic methods using insulin analogs.