FRANCIS J. GRANT,THEODORE E. WHITMORE,SCOTT R. PRESNELL,JANE A. GROSS,STACEY R. DILLON,JULIA E. NOVAK,JOSEPH L. KUIJPER,CINDY A. SPRECHER,ZEREN GAO,MARIA M. DASOVICH,ANGELA K. HAMMOND
申请号:
PT03761891
公开号:
PT1576112E
申请日:
2003.01.21
申请国别(地区):
PT
年份:
2012
代理人:
摘要:
There is provided an isolated multimeric or heterodimeric cytokine receptor comprising: a first polypeptide, wherein the first polypeptide comprises an amino acid sequence having at least 90 percent sequence identity with residues 20-732 of SEQ ID NO:111 or an amino acid sequence having at least 90 percent sequence identity with residues 20-649 of SEQ ID NO:109 and a second polypeptide comprising residues 28-429 of SEQ IDNO:7 wherein the multimeric or heterodimeric cytokine receptor binds a ligand comprising residues 27-164 of SEQ ID NO:2.