To provide pharmaceutically active compound releasing multilayered microparticles in a liquid dosage form.Kind Code: A1 The present invention relates to controlled release multilayered microparticles containing a pharmaceutically active compound, said microparticles being intended for oral administration or direct intragastric administration in the form of a liquid pharmaceutical composition. The present invention also relates to a liquid pharmaceutical composition containing the microparticle, a kit for preparing the liquid pharmaceutical composition, a solid pharmaceutical composition intended to be reconstituted into the form of the liquid composition and a liquid pharmaceutical composition As well.(FIG.【課題】液体剤形中の薬学的活性化合物放出性多層微小粒子の提供。【解決手段】本発明は、薬学的活性化合物を含有する制御放出性多層微小粒子に関し、前記微小粒子は、液体医薬組成物の形態での経口投与又は直接胃内投与を意図したものである。本発明はまた、前記微小粒子を含有する液体医薬組成物、前記液体医薬組成物の調製用キット、前記液体組成物の形態に再構成されることを意図した固体医薬組成物及び前記液体組成物の調製方法にも関する。【選択図】図4
